Dr Holt postulated that radiowaves at the specific frequency of 434 MHz UHF have a non-thermal effect on the physiology of cancer cells, namely increased cell division or some changes in the electrochemistry of cells evidenced by resonance effects. There has been no systematic in-vitro research into these questions and these hypotheses are in the process of being addressed as part of the Radiowave Therapy Research Institute projects.

Increase in cell division

Dr Holt postulated that 434 MHz radiowaves increase the rate of cell division and that this will result in more cancer cells being starved of energy following the administration of GMI. The evidence for this is based on observation of cells pre and post exposure to radiowaves.

Resonance/fluorescence effect

Dr Holt claims to have observed differences in the power spectrum of the radiowave waveform emitted by cancer patients’ bodies during radiowave treatment, compared to the spectrum emanating from people without cancer. The power spectrum, or spectral density, describes the power contribution to a signal at various frequencies. This is measured by a spectrum analyzer (Figure 10).

Dr Holt supported this postulation with the observation that when a tumour decreased in size during the course of a treatment the power spectrum would gradually return to the “normal” unimodal shape.

Dr Holt attributed this difference to an electrical resonance effect in cancer cells when they are stimulated by RF energy, specifically at 434 MHz. In physics resonance is the tendency for a system to oscillate with high amplitude when excited by energy at a certain frequency. This frequency is known as the system’s natural frequency of vibration or resonant frequency. Resonance is a phenomenon found in many mechanical, acoustic and electric systems. This resonance would, he believed, lead to fluorescence, whereby the cancer cells re-radiated the input RF energy at a slightly different output frequency – 434± MHz. The interference between the input and output frequencies created the harmonics observed in the waveform. Fluorescence is a phenomenon in which EM energy (usually at UV wavelengths) is absorbed by a body and reradiated at a longer wavelength.

Dr Holt suggested that the resonance effect could be attributed to some change in the electrical conductivity of malignant cells, although this was not elucidated. Furthermore, Dr Holt postulated that there is a ‘memory effect’ in cancer cells following exposure to RF which allows them to somehow retain this stimulation. He further assessed that this effect peaks 24 hours after the original RF exposure.

Figure 10: Changes in power spectrum. Top: patient without cancer, Middle and bottom: patients with cancer. (Holt, undated Ill. 15, 16 and 17 p. 37)

Penetration depth

The effective penetration depth () is defined to be the depth at which the irradiance (incident power per unit area) has been reduced to a value of about 37%, being the reciprocal of Euler’s constant (e). Hence at a depth of twice the penetration depth there is still about 13% of the incident power (Figure 11). Note that this is a graph of a mathematical function (exponential decay) and is not experimentally measured data.

Figure 11: Decrease in power with tissue depth in fat at 434 MHz assuming exponential decrease. The penetration depth is 15 cm, as reported by Ammann and Curto for 434 MHz in a test phantom.

Measuring RF dose

Irradiance

Irradiance, or power density, measures the amount of power incident on a unit surface area, for example a patch of human skin. It is measured in units of mW / cm2 or equivalently, after multiplying by a factor of ten, in units of W / m2.

The effective penetration depth () is defined to be the depth at which the irradiance (incident power per unit area) has been reduced to a value of about 37%, being the reciprocal of Euler’s constant (e). Hence at a depth of twice the penetration depth there is still about 13% of the incident power (Figure 11). Note that this is a graph of a mathematical function (exponential decay) and is not experimentally measured data.

Figure 11: Decrease in power with tissue depth in fat at 434 MHz assuming exponential decrease. The penetration depth is 15 cm, as reported by Ammann and Curto for 434 MHz in a test phantom.

Specific absorption rate (SAR)

The specific absorption rate (SAR) measures the time rate of absorption of electromagnetic energy by a body. It is measured in W / kg. The SAR can be determined from the electric field strength E in the body or from the rate of temperature rise (t).

Absorbed dose

Absorbed dose refers to the energy deposited in a medium by radiation. It has the units of J/kg, which are given the name gray (Gy). In ionizing radiation the absorbed dose is multiplied by a factor to obtain an equivalent dose measuring the biological effect of the radiation.

## Radiowaves & Cancer Cells

## Radiowaves & Cancer Cells

Dr Holt postulated that radiowaves at the specific frequency of 434 MHz UHF have a non-thermal effect on the physiology of cancer cells, namely increased cell division or some changes in the electrochemistry of cells evidenced by resonance effects. There has been no systematic in-vitro research into these questions and these hypotheses are in the process of being addressed as part of the Radiowave Therapy Research Institute projects.

## Increase in cell division

Dr Holt postulated that 434 MHz radiowaves increase the rate of cell division and that this will result in more cancer cells being starved of energy following the administration of GMI. The evidence for this is based on observation of cells pre and post exposure to radiowaves.

## Resonance/fluorescence effect

Dr Holt claims to have observed differences in the power spectrum of the radiowave waveform emitted by cancer patients’ bodies during radiowave treatment, compared to the spectrum emanating from people without cancer. The power spectrum, or spectral density, describes the power contribution to a signal at various frequencies. This is measured by a spectrum analyzer (Figure 10).

Dr Holt supported this postulation with the observation that when a tumour decreased in size during the course of a treatment the power spectrum would gradually return to the “normal” unimodal shape.

Dr Holt attributed this difference to an electrical resonance effect in cancer cells when they are stimulated by RF energy, specifically at 434 MHz. In physics resonance is the tendency for a system to oscillate with high amplitude when excited by energy at a certain frequency. This frequency is known as the system’s natural frequency of vibration or resonant frequency. Resonance is a phenomenon found in many mechanical, acoustic and electric systems. This resonance would, he believed, lead to fluorescence, whereby the cancer cells re-radiated the input RF energy at a slightly different output frequency – 434± MHz. The interference between the input and output frequencies created the harmonics observed in the waveform. Fluorescence is a phenomenon in which EM energy (usually at UV wavelengths) is absorbed by a body and reradiated at a longer wavelength.

Dr Holt suggested that the resonance effect could be attributed to some change in the electrical conductivity of malignant cells, although this was not elucidated. Furthermore, Dr Holt postulated that there is a ‘memory effect’ in cancer cells following exposure to RF which allows them to somehow retain this stimulation. He further assessed that this effect peaks 24 hours after the original RF exposure.

Figure 10:Changes in power spectrum. Top: patient without cancer, Middle and bottom: patients with cancer. (Holt, undated Ill. 15, 16 and 17 p. 37)## Penetration depth

The effective penetration depth () is defined to be the depth at which the irradiance (incident power per unit area) has been reduced to a value of about 37%, being the reciprocal of Euler’s constant (e). Hence at a depth of twice the penetration depth there is still about 13% of the incident power (Figure 11). Note that this is a graph of a mathematical function (exponential decay) and is not experimentally measured data.

Figure 11:Decrease in power with tissue depth in fat at 434 MHz assuming exponential decrease. The penetration depth is 15 cm, as reported by Ammann and Curto for 434 MHz in a test phantom.## Measuring RF dose

## Irradiance

Irradiance, or power density, measures the amount of power incident on a unit surface area, for example a patch of human skin. It is measured in units of mW / cm2 or equivalently, after multiplying by a factor of ten, in units of W / m2.

The effective penetration depth () is defined to be the depth at which the irradiance (incident power per unit area) has been reduced to a value of about 37%, being the reciprocal of Euler’s constant (e). Hence at a depth of twice the penetration depth there is still about 13% of the incident power (Figure 11). Note that this is a graph of a mathematical function (exponential decay) and is not experimentally measured data.

Figure 11:Decrease in power with tissue depth in fat at 434 MHz assuming exponential decrease. The penetration depth is 15 cm, as reported by Ammann and Curto for 434 MHz in a test phantom.## Specific absorption rate (SAR)

The specific absorption rate (SAR) measures the time rate of absorption of electromagnetic energy by a body. It is measured in W / kg. The SAR can be determined from the electric field strength E in the body or from the rate of temperature rise (t).

## Absorbed dose

Absorbed dose refers to the energy deposited in a medium by radiation. It has the units of J/kg, which are given the name gray (Gy). In ionizing radiation the absorbed dose is multiplied by a factor to obtain an equivalent dose measuring the biological effect of the radiation.